When for whatever reason you cannot see.
Most common causes of Karkand Syndrome are :
- Having a glass eye
- Being Blind
- Playing the map 'Strike at karkand' on Battlefield 2 - Having the draw distance set to -200ft
- Dynasty Warriors.
"I hear he got karkand syndrome after running into a wall of spikes"
"Shit , this fog is so bad its like i have Karkand Syndrome"