An emergency in the ball sack region that requires immediate attention. This usually happens at a time when you can't fixate your balls to a comfortable position because people are around. This includes irritation, itchiness, balls sticking to your leg, and of course, your balls just feeling weird. Also commonly referred to as just "Ned's".
John: Damn, I have a Ned's.*Fixates balls.*
Alex: ...*Fixates balls*
Jimmy: I have a Ned's Declassified, but I don't care, I'll scratch it in front of people.
Jake(Has no balls): Oh yeah, me too.