Shorthand for "Gimpy Couple". A romantic couple with a high combined "geek" factor. They tend to stay indoors and have few friends. To qualify for Gupple status, the couple must be fairly cute, but not too pitiful.
Dick is a hacker nerd and Jane is a gamer chick, they make a cute Gupple as they drink Bawls at the Anime convention. They brush each other's braces afterwards.