A man or woman who feels that he or she was born into the wrong gender. The man or woman most likely has the personality of the opposite gender, and feel they cannot relate to their own gender. Also, someone who has undergone surgery to become the opposite gender they yearned to be.
I. I've always had a desire to be a man; I am a transsexual.
II. David used to be Delilah- he is a transsexual.
A short term for SiriusxRemus. Sirius Black and Remus Lupin being characters from Harry Potter. This is a relationship that is thought to be clearly canon in the books, and many fan fictions and pictures are based on the two boys.
I read a fanfic about SxR the other day where Sirius writes a note to Remus about how he loves him during their school years.