1 definition by Jennica Starlight

Top Definition
In reference to Trisomy 21 where there is 3 genetic materials on the 21st chromosome instead of the usual 2. This causes Down's Syndrome.
He never really understnads what is happening.I think he's a little 3 on the 21. Started in Canada in 2004.
by Jennica Starlight November 30, 2004

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