1 definition by ILoveLamp12!

Top Definition
The term uppers is a street name for amphetamine-based psychostimulant drugs that produce increased wakefulness and focus, in association with decreased fatigue and appetite. Also referred to as speed, uppers are widely used recreationally as a performance enhancer for athletes and college students, and abused as a weight-loss supplement. In the United States, uppers are also consumed as a prescription to treat ADD (Attention Deficit Disorder) and ADHD (Attention Deficit Hyperactivity Disorder). Examples of these include the brand-named medications Adderall, Dexedrine, Dextrostat, Desoxyn, ProCentra, and Vyvanse, as well as Benzedrine in the past (due to high recreation use as early as the 1940's).

Other narcotic such as MDMA (ecstasy), methamphetamine (meth), and cocaine can also be colloquially referred to as uppers.
"Hey, could I buy uppers from you? I have a huge paper to write tonight."
by ILoveLamp12! April 27, 2012

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