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2 definitions by Greatest EVR

Its an acronym for GET THE FUCK OUT!
Bitch you gettin on my nerves your gonna have to GTFO!
by Greatest EVR August 18, 2010
A grenade is what the fat ugly bitch that is with a group of fine ass women is called. If she gets upset then it "blows up" the time for the rest of the girls in the group or the guys trying to get with them.
Dude go lay on that Grenade for us she is about to get pissy and its gonna fuck it up for all of us!
by Greatest EVR August 18, 2010