1. an acronym standing for "Prisoner of Fat", when a persons genitals are unable to be seen from a natural standing position, due to when one's line of sight is obstructed by their own morbid obesity.
2. an acronym standing for "Prisoner of Foreskin" when a male is uncircumcised.
Wow, i could never sleep with a POF ewwww.
Thanks for not being a POF POF.
OMG what it the guy you liked was a POF, would you dump him???
Wow, look at how fat he is, he must be a POF