The commonly accepted abreviation for Hagane no Renkinjutsushi (Fullmetal Alchemist)
A popular Japanese anime following the adventure of two brothers, Edward and Alphonse Elric who commit the ultimate taboo of trying to revive their dead mother with alchemy. The transmutation fails, resulting in the loss of Ed's left leg and right arm, and Al's entire body. The two set out (Ed now equiped with prosthetic limbs and Al now merely a soul housed in a suit of armor)in search of the legendary Philosopher's Stone in the hopes of restoring their bodies to normal.
See also: Full Metal Alchemist
and Fullmetal Alchemist