Effectively, when a man has been "fucked" by a woman...metaphorically speaking, of course.
Emotionally the equivalent of being kicked in the testicles...everyday (because you see the person who's the reason why you're in the friend zone everyday, don't you?).
As of now, modern science has been unable to find a cure.
As used in this sentence, "At least I'm not in the Friend
Zone, like that idiot over there."
In this unfortunate situation, the guy is mistaken on both counts: 1) he is in the Friend Zone, BAD, cuz he doesn't even know what the hell's going on, and 2) the other guy he is refering to is a bad example, because he is obviously gay, and therefore has no sexual feelings for the women he is around, and is more acurately placed in the lesser known or traversed, "GirlFriend
Zone". Currently, no known straight male has yet been this far gone, so very little is available about this terrifying area.