1. In Baseball or Softball, to achieve a home run by hitting the ball so hard that not even the player who stayed home with his sick kids could catch it.
2. A single hit that is so vicious that its effects are felt for a while afterwards, usually through flying backwards, falling to the ground, writhing in pain, and throwing up. Bonus points if you do it with a baseball bat.
Aaron tried to sneak up on me while I was blindfolded, but I kicked him in the groin, which caused him to be knocked out of the park.
A moron's way of censoring fuck, in order to get around online censors. The funny thing is, most censors will catch poor fsck, but won't catch f*ck. It's seen quite often on popular sites that don't even have censors.
I need to curse, but why bother reaching for the asterick? FSCK!