The act of spoiling the mood atmosphere or fun of others, intentionally or not, usually at a club or party.
1-Steve: Dude, the girl I'm tryin to get with keeps dancing with that other guy, what the hell?
Brad: Yea, this club sucks. Let's kill the scene and get outta here.
2-Jen: oh jeez, here comes that dorky tom kid. He's totally gonna kill the scene.