1 definition by Dr Shea Foster, DDR

Top Definition
A disease common to people born below the Mason-Dixon line, which restricts each individual's IQ to less than the number of teeth they have. Also referred to as MDLS
So I was watching COPS, and they pulled over a guy with a joint behind his ear. He had a major case of Mason-Dixon Line Syndrome.
by Dr Shea Foster, DDR December 19, 2008

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