To suffer from intestinal discomfort. Also known as gutrot or gut rot. Can be treated with plenty of water and replacement salts to ensure no dehydration occurs from the common side effect - the shits.
The term is most commonly used in the North West of England around Manchester and Lancashire. Predominantly by the older generation who are less likely to use the more common vulgar terms in use by modern society.
"Christ - I've got the gripe!!"
"I can tell am gonna be shitting through the eye of a needle later - I've got the gripe."