1. Heroine cut with low grade substances such as comet, ajax, talcum powder, powdered sugar or a mixture of substances. The term comes from the 1960's and 70's. It has also been applied to other drugs, such as methamphetamine.
2. A woman and sometimes a man who is or has been strung out on skank heroine or more recently a chronic user of methamphetemine. Sometimes called a skank-ho.
Skank: Heroine, a heroine addict, a methamphetamine addict. Someone who performs sexual acts for drugs.