A "Skunktail"(suppository pill filled with kief) laced with PCP, LSD, Roofalin, and over-the-counter laxatives. Rendering the victim helpless, paranoid, disassociated, and covered in feces. Spikers are used to achieve a drug facilitated sexual assault. Spiker became a household name when several Bathhouse visitors came forward in the mid 90's of being sexually assaulted.
It's also been known as "spiking" and/or "getting spiked".
Guy 1: Did you hear about John?
Guy 2: Yeah, someone gave him a Spiker and at The White Dove. He thought it was a Skunktail. Get this, he lost all his money, his ID, and most of his clothes.
Guy 1: Is he still shitting?
Guy 2: Hasn't stopped.