1. Substitute for 'Fucking', with most of the same applications in common usage and with much the same vulgarity, but you can probably get away with saying it in front of your parents.
Popularized on the television series Firefly and its motion picture incarnation Serenity.
"I think I know the answer, Mr. Garrison!"
"Shut up, fatass!"
"Don't you tell me to shut up, you ruttin' Jew!"
"Eric! Did you just say the 'R word'?!"