As implied. The risk of catching an STD from a sexual encounter because the other person is a whore. Could also be used as a scale from one to ten or as a probability. One being the lowest, ten being he highest.
That girl is so dime, I would hit it but she's whore and I wouldn't take the std risk.
I would bang that skank but even double baggin it wouldn't be worth the STD risk.
Wow! Look at that girl dancing on the bar. What a Skankzilla. STD risk - 10 or STD risk - 100%.