A phrase used to articulate feelings of immense loathing of someone that is known for unintelligent or troublesome actions. The phrase being used when a particular action comes into play. Usually followed by a facepalm.
Origin: First used in season 4 of "Futurama", episode 68 - "Obsoletely Fabulous". Bender, because of his new found hatred for advanced technology, has had a downgrade, making him a wooden, steam-powered robot. Bender enters the scene and Leela immediately exclaims "Oh brother, he's made of wood."
Leroy: "Is that Clyde over there?"
Jeff: "Dammit, I think so. What's he up to this time?"
Clyde: "Hey Jeff! Check it out! I found this guy down at the hospital on 42nd street! He seems pretty cool! Check out his cool bracelet!"
Leroy: "Isn't that 'hospital' a personal care home for the mentally ill?"
Jeff: "Oh brother, he's made of wood."