Getting screwed, fucked over, going on a canoe trip. An acronym meaning "They're fucking me," often used in workplace environments where foul language is prohibited or discouraged. "They" often refers to a variety of people, including inexperienced management, college graduate management hires, total morons, the cops, the feds, most government agents, alien lifeforms, and Chuck Norris. TFM can be used in its acronym form or as a verb.
Scott: TFM brother, hope it's time to go home soon!
Matt: Indeed. I don't think I can keep getting TFM'd any longer!
Caleb: Are they TFMing you guys too?
Scott & Matt: Yeah, big time TFM!