It can mean any and everything it just depends on how you say it. The meaning is determined by what the conversation was leading too before the word was used or by the fluctuation on how it was said. It also means to throw.
Dude look at the chick. Man, she is thrown!
Dude look at the chick. Man, she is HOT!
I was soo thrown last night.
I was soo WASTED last night.