having had sexual relations with a slut or unattractive person, no longer making them available to hook up with
"Daaaamn, chris looks good, i'd hit!"
"Girl what? you can't hook up with him, he's not sterile! He hooked up with sarah last weekend"
"Oh fasho, not tryin to get chlamydia"
© 1999-2015 Urban Dictionary ®
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