Same aspect to "blue balls," but in female form. When a girl almost fullfills her sexual peak but some asshole decides to cut her short from orgasm. Usually, this type of girl is the shit because she can over-ride the power of how men feel when they get blue nasty balls.
John: Yo I was going down on Steph last night and when I stopped she went ape-shit on me.
Chris: Did she orgasm?
John: No, why?
Chris: No wonder dude, you're such an idiot, you gave her blue vagina!