1 definition by Bizzle187

Top Definition
The main highway in Houston used by most people to commute to work or go downtown...often referenced in a lot of houston rapper's songs such as Paul Wall, Mike Jones, Slim Thug...the word is orally pronounced "Five-Nine"
Sittin on that 59 South baby, PO'D up off dat texas tea
by Bizzle187 July 22, 2006

Free Daily Email

Type your email address below to get our free Urban Word of the Day every morning!

Emails are sent from daily@urbandictionary.com. We'll never spam you.