1 definition by BallsDeepInShiva

Top Definition
A disease in which a female thinks that she is attractive but actually she is the opposite.
Why does she dress like that?" "Ya she is not even a 4." "I guess she has Marge Syndrome.
#marge #syndrome #ms #ugly girl thinks she is cute #annoying
by BallsDeepInShiva February 13, 2011
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