1 definition by AmyhatesTwilight

Top Definition
A disease affecting the brain of adolescent females, particularly the frontal and occipital lobes. Symptoms include lost sense of reality, hallucinations of Edward Cullen, belief that vampires are real, and general idiocy.

If a person is suspected of having Twilight Syndrome, they should immediately be quarantined and made to read the Harry Potter series for 250 hours straight in a silent, white room with no food. With luck, the victim will either come to their senses and remember how to be a real human being, or they will die.
Julie: All of my friends say that Twilight is better than Harry Potter! I fear for their minds.

Amy: Oh no! They must have Twilight Syndrome, alert the government!
by AmyhatesTwilight August 04, 2008

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