1. A slice of homey-ness
2.A friend/amigo. One who you are "tight" with
1. Murphy : Mildred, why did we throw out that old sofa?
Mildred : Because it was old dear...
Murphy : But it was a homeslice!
2. Wannabe G 1: YO YO! What up G-dog?
Wannabe G 2: Aww nuthin homeslice, jus chillin...