Contrary to what the other definition for this term may say, "spice" generally does not refer to 2C-I or any other 2C-x compound for that matter. Usually when one refers to "spice" they are talking about N,N-Dimethyltryptamine (DMT), the powerful and short acting psychedelic often smoked in base form or taken orally with an MAOI.
"I loaded some spice into my pipe and took a dive into hyperspace"
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