To get so pissed that your primal instincts take over and you just don't give a shit anymore, and tell the person or persons how you really feel.
Could also lead to violence , but for the most part "Wolfing Out" is just to be vocal about how you are feeling (like a wolf howling ).
The total opposite of freak out or freaking out.
Example 1. Man that fuckhead keeps spreading rumors about me to everyone on campus, I'm about to go over there and wolf out on him!
Example 2. Do you see that guy over there, he is totally wolfing out
on that bitch!